Histopathology

21 Gestational Weeks Inferior Hippocampal Formation colabeled with Calbindin, PCP4 and Calretinin

21 Gestational Weeks Inferior Hippocampal Formation colabeled with Calbindin, PCP4 and Calretinin

Adult Human Brain Cerebellum H&E stain

Adult Human Brain Cerebellum H&E stain

Adult Human Brain Cerebellum Nissil stain

Adult Human Brain Cerebellum Nissil stain

Adult Human Brain Myelin Stain

Adult Human Brain Myelin Stain

Adult Human Brain- Cerebellar Purkinje Cells

Adult Human Brain- Cerebellar Purkinje Cells

Adult Human Brainstem Immunostained for Neurofilament H

Adult Human Brainstem Immunostained for Neurofilament H

Fetal Brain H&E stained

Fetal Brain H&E stained

Fetal Brain Hippocampal Formation Nissil Stain

Fetal Brain Hippocampal Formation Nissil Stain

Fetal Brain Nissil Stain

Fetal Brain Nissil Stain

Reactive astrocytes in Ischemic stroke - GFAP IHC

Reactive astrocytes in Ischemic stroke - GFAP IHC

Computational

Zero Footprint Viewer

This tool enables viewing of microscopically scanned brain images at ultra-high resolution without loss of quality. It supports visualisation of 20 µm brain sections scanned at resolutions as fine as 0.5 µm.

Zero Footprint Viewer

Atlas Creator

This tool supports geometry-based annotation of regions on high-resolution microscopic brain images. It allows creation, saving, display, and sharing of multiple region-specific annotations across users.

Atlas Creator

Cell Annotation Tool

This tool enables pixel-level manual annotation of cells on brain images. It supports machine-learning–based cell detection through high-quality training annotations.

Cell Annotation Tool

Registration (Manual & Automatic)

This tool aligns images from different modalities, time points, or subjects to a common coordinate system. It supports precise spatial correspondence for comparative analysis and integration.

Registration (Manual & Automatic)

Series Viewer

This tool facilitates exploration and analysis of large image series. It enables interactive inspection for identifying patterns and trends across datasets.

Series Viewer

Technology & Engineering

Brain Freezing

This technology platform enables freezing of large human brains in stereotaxic coordinates with minimal tissue damage and artifacts. It ensures preservation of anatomical integrity for downstream histological processing.

Brain Freezing

Slot Die Coater

This automated system applies a uniform 10–20 µm thin adhesive layer on glass slides. It preserves tissue integrity during tape-transfer cryo-sectioning.

Slot Die Coater

Automated Tissue Transfer

This automated system performs cryo-sectioning and transfers tissue onto glass slides with minimal tissue damage. It ensures consistent and reliable section handling.

Automated Tissue Transfer

Block Face Imaging

This system serves as an intermediate step in the histopathology pipeline for imaging tissue blocks. It enables detection of structural and volumetric changes in the brain.

Block Face Imaging

UV Curing Station

This system enables hands-free and tool-free transfer of 20 µm thick tissue sections onto glass slides. The transfer is achieved through controlled UV exposure.

UV Curing Station

Large Format Autostainer

This custom-built automated staining system processes tissues mounted on multiformat slides (6×8, 5×7, 2×3, and 1×3). It ensures staining uniformity and consistency across formats.

Large Format Autostainer

Large Format Coverslipper (6×8)

This automated system performs uniform, bubble-free coverslipping of 6×8 slides. It supports a throughput of up to 30 slides per hour.

Large Format Coverslipper (6×8)

Automated Coverslipper (2×3)

This fully automated system performs coverslipping of 2×3 slides. It supports high-throughput operation of up to 50 slides per hour.

Automated Coverslipper (2×3)

Monitoring Dashboard

This system monitors critical laboratory operations, including environmental parameters, coverslipping, and staining. It generates reports and alerts users during failures.

Monitoring Dashboard

Scanning Station

These custom whole-slide scanners digitise multiformat slides at 0.5 µm per pixel resolution. They are developed in collaboration with an indigenous company.

Scanning Station